Mumakore ekuma1990, nyanzvi dzezvokurapa dzeSwitzerland dzakaona kuti maplatelet anogona kubudisa nhamba huru yekukura kwezvinhu pakakwirira, iyo inogona kukurumidza uye inobudirira kugadzirisa maronda emaronda.Zvadaro, PRP yakashandiswa mukuvhiya kwakasiyana kwemukati nekunze, kuvhiyiwa kwepurasitiki, kuisirwa ganda, nezvimwe.
Isu takambotanga kushandiswa kwePRP (Platelets Rich Plasma) mukugadzirwa kwebvudzi kubatsira kupora maronda uye kukura kwebvudzi;Zvechokwadi, kuedza kunotevera kuedza kuwedzera kuvharwa kwebvudzi rekutanga nekubaya PRP.Ngationei kuti ndezvipi mhedzisiro ichawanikwa nekubaya autologous platelet yakapfumisa plasma uye zvakasiyana-siyana kukura zvinhu muvarume varwere vane alopecia, inovawo kurapa kwatingatarisira kushandisa kurwisa kurasikirwa kwebvudzi.
Pamberi uye panguva yese yekugadzirwa kwebvudzi, varwere vanobatwa nePRP uye avo vasina kubaiwa nePRP vanogona kuita kuti bvudzi rikure nekukurumidza.Panguva imwecheteyo, munyori akakurudzirawo chidzidzo chekusimbisa kana platelet yakapfuma plasma ine mhedzisiro yakafanana pakuvandudza bvudzi rakanaka.Ndeupi rudzi rweronda rinofanira kushandiswa uye yakawanda sei yekukura chinhu inofanira kubaiwa zvakananga kuti ibudirire?PRP inogona kudzoreredza kutetepa zvishoma nezvishoma kwebvudzi mu androgenic alopecia, kana kuti inogona kunyatso kurudzira kukura kwebvudzi kuvandudza androgenic alopecia kana zvimwe zvirwere zvekurasa bvudzi?
Mumwedzi misere iyi yekuedza kudiki, PRP yakaiswa mumusoro we androgenic alopecia uye alopecia zvidzidzo.Kuenzaniswa neboka rinodzora, rinogona kudzoreredza kutetepa zvishoma nezvishoma kwebvudzi;Mukuwedzera, kana ijekiseni muvarwere vane mhanza yakatenderera, bvudzi idzva rinokura rinogona kuonekwa mwedzi mumwe gare gare, uye mhedzisiro yacho inogona kugara kwemwedzi inopfuura misere.
Nhanganyaya
Muna 2004, apo mumwe wevatsvakurudzi akabata chironda chebhiza nePRP, vanga racho rakaporeswa mukati memwedzi mumwe uye bvudzi rakakura, uye ipapo PRP yakashandiswa pakuvhiyiwa kwebvudzi;Vatsvakurudzi vakaedzawo kupinza PRP pamusoro peganda revamwe varwere vasati vagadziriswa bvudzi, uye vakaona kuti vhudzi revarwere raiita kunge rakawedzera (1).Vatsvagiri vanotenda kuti revascularization uye mhedzisiro yeyakakwira yekukura chinhu inogona kukurudzira kukura kwebvudzi follicle masero mumusoro wenzvimbo isingashande.Ropa rinonyatsogadziriswa.Maplatelet anoparadzaniswa kubva kune mamwe mapuroteni eplasma uye ane huwandu hwakawanda hwemaplatelet.Kuti usvike pachiyero chemaitiro ekurapa, kubva pa1 microliter (0.000001 litre) ine 150000-450000 maplatelet kusvika 1 microliter (0.000001 litre) ine 1000000 maplatelet (2).
Platelet α ine marudzi manomwe ekukura kwezvinhu mumagranules, anosanganisira epithelial growth factor, fibroblast growth factor, thrombogen growth factor and transforming growth factor α, Interleukin-1, uye vascular endothelial growth factor (VEGF).Mukuwedzera, antimicrobial peptides, catecholamines, serotonin, Osteonectin, von Willebrand factor, proaccelenn nezvimwe zvinhu zvinowedzerwa.Zvimedu zvakakora zvine marudzi anopfuura zana ekukura kwezvinhu, izvo zvinogona kuita pamaronda.Pamusoro pekukura kwezvinhu, iyo yakasarudzika platelet sparse plasma (PPP) ine matatu cell adhesion molecules (CAM), Fibrin, fibronectin, uye vitronectin, puroteni inoshanda yakawanda inomisa chimiro chikuru uye matavi kudzora kukura kwesero, kunamatira, kupararira, kusiyanisa uye kuberekwa patsva.
Takakura, et al.yakataura kuti iyo PDCF (platelet derived growth factor) chiratidzo chine hukama nekudyidzana kweepidermal hair follicles uye dermal stromal masero, uye inodiwa pakuumbwa kwebvudzi ducts (3).Muna 2001, Yano et al.yakaratidza kuti VFLGF inonyanya kudzora kutenderera kwebvudzi rekukura, ichipa humbowo hwakananga hwekuti kuwedzera bvudzi follicle vascular reconstruction kunogona kukurudzira kukura kwebvudzi uye kuwedzera bvudzi follicle uye saizi yebvudzi (4).
PS: Platelet inotorwa kukura chinhu, PDCF.Chinhu chekutanga chekukura chakabvumidzwa neUS FDA kurapa chisingaperi kukuvara kweganda ndiyo yekutanga kukura chinhu chinoburitswa nekukurudzira mushure mekukuvara kweganda.
PS: Vascular endothelial kukura chinhu, VEGF.Icho chimwe chezvinhu zvakakosha zvinogadzirisa zvinogadzirisa endothelial cell proliferation, angiogenesis, vasculogenesis uye vascular permeability.
Kana tichitenda kuti kana nhunzvatunzva dzebvudzi dzaserera zvokuti hatigoni kuona kukura kwebvudzi neziso rakashama, pachine mukana wokuti mvere dzikure (5).Mukuwedzera, kana vhudzi rebvudzi rebvudzi rakanaka rakafanana nerebvudzi rakaoma, kune masero e stem akakwana mu epidermis uye bulge (6), zvinokwanisika kuita kuti vhudzi rive rakatetepa uye rakakura mumhanza yevarume.
Nguva yekutumira: Zvita-20-2022